Peer-reviewed publications
2010
Olivier Vallat, Ana-Maria Buciumas, Reinhard Neier and Helen Stoeckli-Evans
J. Chem. Cryst 2010, 40, 10-14.
2009
Carine Eng, Jean-Mary Simone, Akane Hartenbach, François Loiseau, Reinhard Neier
Monatshefte für Chemie 2009, 140(3), 349-354.
rac Methyl 4-azido-3-hydroxy-3-(2-nitrophenyl)butanoate
Olivier Vallat, Ana-Maria Buciumas, Reinhard Neier and Helen Stoeckli-Evans
Acta Cryst. E: Structure Reports Online 2009, E65(2), o396-o397.
5-Hydroxyalkyl Derivatives of tert-Butyl 2-oxo-2,5-dihydro-1H-pyrrole-1-caboxylate
Olivier Vallat, Ana-Maria Buciumas, Reinhard Neier and Helen Stoeckli-Evans
Acta Cryst. C : Crystal Structure Communications 2009, C65(4), o171-o175.
Synthesis, structure, and complexation properties of partially and completely reduced meso-octamethylporphyrinogens (calix[4]pyrroles).
Valeria Blangy, Christophe Heiss, Vsevolod Khlebnikov, Christophe Letondor, Helen Stoeckli-Evans
and Reinhard Neier
Angewandte Chemie, International Edition 2009, 48(9), 1688-1691.
2008
Carole Pissot Soldermann, Ramakrishnan Vallinayagam, Manuel Tzouros, Reinhard Neier
J. Org. Chem 2008, 73, 764-767. .
Glycoside Esters of 5-Aminolevulinic Acid for Photodynamic Therapy of Cancer
Ramakrishnan Vallinayagam, Frederic Schmitt, Jerome Barge, Georges Wagnieres, Virginie Wenger, Reinhard Neier, Lucienne Juillerat-Jeanneret
Bioconjugate Chemistry (2008), 19(4), 821-839.
Novel Bioconjugates of Aminolevulinic Acid with Vitamins
Ramakrishnan Vallinayagam, Joanne Weber, Reinhard Neier
Organic Letters 2008, 10(20), 4453-4455.
Novel Bioconjugates of Aminolevulinic Acid with Nucleosides
Patrice Gurba, Ramakrishnan Vallinayagam, Frédéric Schmitt, Julien Furrer, Lucienne Juillerat-Jeanneret, Reinhard Neier
Synthesis 2008, (24), 3957-3962.
2007
Radical Couplings as Key Steps for the Preparation of Derivatives of Nonactic Acid.
Francois Loiseau, Jean-Mary Simone, David Carcache, Pavel Bobal, Reinhard Neier
Monatshefte fuer Chemie 2007, 138(2), 121-129.
Jean-Mary Simone, Francois Loiseau, David Carcache, Pavel Bobal, Julie Jeanneret-Gris, Reinhard Neier
Monatshefte fuer Chemie 2007, 138(2), 131-139.
Synthesis of bisubstrate inhibitors of porphobilinogen synthase from Pseudomonas aeruginosa.
Sabine Gacond, Frederic Frere, Merle Nentwich, Jean-Philippe Faurite, Nicole Frankenberg-Dinkel, Reinhard Neier
Chemistry & Biodiversity 2007, 4(2), 189-202.
The High Stereoselectivity of the Tandem Sequence Diels-Alder Reaction/Ireland-Claisen Rearrangement Starting from Substituted O-(E)-Buta-1,3-dienyl Ketene Acetals and Cyclic Dienophiles
Nicolas Soldermann, Jörg Velker, Antonia Neels, Helen Stoeckli-Evans, Reinhard Neier
Synthesis 2007, 2379-2387.
Synthesis of Novel and Stable 5-Aminolevulinic Acid Derivatives fort he Efficient Synthesis of 5-Aminolevulinic Acid Based Prodrugs
Ramakrishnan Vallinayagam, Hugo Bertschy, Yann Berger, Virginie Wenger, Reinhard Neier
Synthesis 2007, 3731-3735.
2006
Probing the Active Site of Pseudomonas aeruginosa Porphobilinogen Synthase Using Newly Developed Inhibitors.
F. Frere, M. Nentwich, S. Gacond, D. W. Heinz, R. Neier, N. Frankenberg-Dinkel
Biochemistry 2006, 45(27), 8243-8253.
2005
Structure of yeast 5-aminolaevulinic acid dehydratase complexed with the inhibitor 5-hydroxylaevulinic acid
P.T. Erskine; L. Coates; R. Newbold; A.A. Brindley; F. Stauffer; G.D.E. Beaven; R. Gill; A. Coker; S.P. Wood; M.J. Warren; P.M. Shoolingin-Jordan; R. Neier, J.B. Cooper
Acta Crystallographica, Section D: Biological Crystallography 2005, 61(9), 1222-1226.
2003
Origins of Boat or Chair Preferences in the Ireland-Claisen Rearrangements of Cyclohexenyl Esters: A. Theoretical Study
Khaledy, Mahmood M.; Kalani, Mohammad Y.S., Khuong, Kelli S.; Houk, K.N.; Aviyente Viktorya; Neier, Reinard; Soldermann, Nicolas; Velker, Joerg
Journal of Organic Chemistry 2003, 68(2), 572-577.
An efficient synthesis of 10-substituted benzo[b]phenantro[9,10-d]furans
L. Cires; V. Botomei; I. Humelnicu; H. Ofenberg; R. Neier
Revue Roumaine de Chimie 2003, 48, 33-37.
2002
Species-specific Inhibition of Porphobilinogen Synthase by 4-Oxosebacic Acid
E.K. Jaffee, J. Kervinen, J. Martins, F. Stauffer, R. Neier, A. Wlodawer, A. Zdanov
J. Biol. Chem. 2002, 277, 19792-19799.
Structure of Porphobilinogen Synthase from Pseudomonas aeruginosa in Complex with 5- Fluorolevulinic Acid Suggests a Double Schiff Base Mechanism
F. Frere, W.-D. Schubert, F. Stauffer, N. Frankenberg, R. Neier, D. Jahn, D.W. Heinz
J. Mol. Boil. 2002, 320, 237-247.
2001
F. Stauffer, E. Zizzari, C. Soldermann-Pissot, J.-P. Faurite, R. Neier
Chimia 2001, 55, 314- 319.
Inhibition Studies of Porphobilinogen Synthase from Escherichia coli. Differentiating between the Two Recognition Sites
F. Stauffer, E. Zizzari, C. Engeloch-Jarret, J.-P. Faurite, J. Bobalova, R. Neier
ChemBioChem 2001, 2, 343 - 354.
Mechanistic Basis for Suicide Inactivation of Porphobilinogen Synthase by 4,7-Dioxosebacic Acid, an Inhibitor That Shows Dramatic Species Selectivity
J. Kervinen, E.K. Jaffe, F. Stauffer, R. Neier, A. Woldawer, A. Zdanov
Biochemistry 2001, 40, 8227 - 8236.
The X-ray structure of yeast 5-aminolaevulinic acid dehydratase complexed with two diacid inhibitors
P.T. Erskine, L. Coates, R. Newbold, A.A. Brindley, F. Stauffer, S.P. Wood, M.J. Warren, J.B. Cooper, P.M. Shoolingin-Jordan, R. Neier
FEBS Letters 2001, 503, 196 - 200.
2000
Application of the Novel Tandem Process Diels-Alder Reaction/Ireland-Claisen Rearrangement to the Synthesis of rac-Juvabione and rac-Epijuvabione
N. Soldermann, J. Velker, O. Vallat, H. Stoeckli-Evans, R. Neier
Helv. Chim. Acta 2000, 83, 2266 - 2276.
Synthesis of Tri- and Tetrasubstituted Furans Catalyzed by Trifluoroacetic Acid
F. Stauffer, R. Neier
Organic Letters 2000, 2, 3535 - 3537.
Ethylene Glycol and Amino Acid Derivatives of 5-Aminolevulinic Acid as new Photosensitizing Precursors of Protoporphyrin IX in Cells
Y. Berger, A. Greppi, O. Siri, R. Neier, L. Juillerat-Jeanneret
J. Med. Chem. 2000, 43, 4738 - 4746.
1999
1998
Influence of the nature and substitution of chiral 2,3-epoxy alcohol derivatives on the enantiomeric elution order on Chiracel OD column
C. Zedde, K. Nacro, J.-M. Escudier, M. Baltas, L. Gorrichon, R. Neier
Chirality, 1998, 10, 804-807
1996
Tandem Cycloadditions of N,O-Ketene N-1,3-Butadienyl-N-alkyl-O-silylacetals with C60: a Straightforward Stereoselective Synthesis of Bicyclic Derivatives of 1,2,3,4-Tetrahydrobuckminsterfullerene
A. Franz, Y.-Z. An, P.S. Ganapathi, R. Neier, Y. Rubin
Proc. Electrochem. Soc. (Recent advances in the Chem. and Physics of Fullerenes, vol. 3) 1996, 3, 1326
1993
1992
Assessment of the Active-Site Requirements of 5-Aminolaevulinic Acid Dehydratase: Evaluation of Substrate and Product Analogues as Competitive Inhibitors
R. M. Lüönd, J. Walker, R. Neier
J. Org. Chem. 1992, 57, 5005
1990
1989
Variation of [2 + 2]- and [4 + 2]-cycloadditions
"Habilitationsschrift"
R. Neier
Multiprint 1989
1988
1987
1986
1983
Unimolecular Dissociations of Excited C3H6O+
R. Bombach, J. Dannacher, E. Honegger, J.-P. Stadelmann and R. Neier
Chem. Phys. 82, 459 (1983)
Fundamental Aspects of Ionic Dissociations: The Fragmentation Pathways of Excited Bicyclobutane Cations
R. Bombach, J. Dannacher, J.-P. Stadelmann and R. Neier
Helv. 66, 707 (1983)
1979
Biosynthesis of Vitamin B12: Structure of Trimethylisobacteriochlorin from Propionibacterium shermanii
A.R. Battersby, G.W.J. Matcham, E. McDonald, R. Neier, M. Thompson, W.-D. Woggon, V.Y. Bykovsky and H.R. Morris
J.C.S. Chem. Comm. 1979, 185
Biosynthesis of Vitamin B12: Experiments on Loss of C-20 from the Precursur Macrocycle
N.G. Lewis, R. Neier, G.W.J. Matcham, E. McDonald and A.R. Battersby
J.C.S. Chem. Comm. 1979, 541
Biosynthesis of Vitamin B12: Isolation and Proof of Structure of 3-Episirohydrochlorin
A.R. Battersby, E. McDonald, R. Neier and M. Thompson
J.C.S. Chem. Comm. 1979, 960
1978
R. Neier
Diss. ETH 6178 (1978)
1977
Photochemical and non-photochemical A/D-secocorrin+corrin-cyclisation
A. Pfaltz, N. Bühler, R. Neier, K. Hirai und A. Eschenmoser
Helv. 60, 2653 (1977)