A Chemical Synthesis of Porphobilinogen Imitating the Pathway Proposed by Shemin for the Biosynthesis: Comparing Inhibition Studies with Investigations of Chemical Reactivity

Abstract

Introduction

Development of a potentially biomimetic methodology

Chemical Synthesis of Porphobilinogen

Conclusions

References and Notes

Pavel Bobál, André Chaperon, Antonia Neels*, Helen Stoeckli-Evans* and Reinhard Neier
Institut de Chimie de l'Université de Neuchâtel,
CH-2000 Neuchâtel
E-mail: Reinhard.Neier@ich.unine.ch

* For questions concerning the X-ray structures please contact:

Service de Crystallographie - BENEFRI
Institut de Chimie de l'Université de Neuchâtel,
CH-2000 Neuchâtel
E-mail: Helen.Stoeckli-Evans@ich.unine.ch